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GET3 antibody

Product Specifications

Background

This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER) . It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.

Synonyms

ATPase GET3|Arsenical pump-driving ATPase|Arsenite-stimulated ATPase|Guided entry of tail-anchored proteins factor 3, ATPase|Transmembrane domain recognition complex 40 kDa ATPase subunit|hARSA-I|hASNA-I|GET3|ARSA|ASNA1|TRC40

Gene ID

439

UniProt

O43681

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

Target

GET3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

39 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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