GET3 antibody
Product Specifications
Background
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.
Synonyms
ATPase GET3|Arsenical pump-driving ATPase|Arsenite-stimulated ATPase|Guided entry of tail-anchored proteins factor 3, ATPase|Transmembrane domain recognition complex 40 kDa ATPase subunit|hARSA-I|hASNA-I|GET3|ARSA|ASNA1|TRC40
Gene ID
439
UniProt
O43681
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Target
GET3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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