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Rorc Antibody - N-terminal region : Biotin (ARP37127_P050-Biotin)

Selected Variant

ARP37127_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

RAR-related orphan receptor gamma

Gene Aliases

Th, ROR, TOR, Thor, Nr1f3, RORgamma

Gene ID

19885

Swiss Prot

P51450

Accession Number

NP_035411

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Rorc is an orphan nuclear receptor. Isoform 2 negatively regulates expression of TNFSF6/FASL and IL2 production in T-cells. It also binds to the TEA promoter and may participate in the regulation of DNA accessibility in the TCR-Jalpha locus.

Partner Proteins

Cul3; Chd4; Ewsr1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 85%; Guinea Pig: 79%; Human: 79%; Mouse: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

Shipping Conditions

Wet Ice

Protein Length

516

NCBI Gene Symbol

RORC

NCBI GB Accession Number

Rorc

Host or Source

Rabbit

Protein Name

Nuclear receptor ROR-gamma

Nucleotide Accession Number

NM_011281

Peptide Sequence

VKFGRMSKKQRDSLHAEVQKQLQQQQQQEQVAKTPPAGSRGADTLTYTLG

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