Eftilagimod alfa
Product Specifications
UNSPSC Description
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research[1].
Target Antigen
LAG-3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eftilagimod-alfa.html
Purity
95.98
Solubility
H2O
Smiles
[Eftilagimod alfa]
References & Citations
[1]Atkinson V, et al. Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma. J Immunother Cancer. 2020 Nov;8(2):e001681.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99933/Eftilagimod-alfa-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99933/Eftilagimod-alfa-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1800476-36-1
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