Micafungin

Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

Product Specifications

CAS Number

[235114-32-6]

Product Name Alternative

FK463

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/micafungin.html

Purity

98.91

Solubility

10 mM in DMSO

Smiles

O=C([C@](NC(C(NC([C@@](C[C@@H](O)C1)([H])N1C2=O)=O)[C@H](O)[C@H](C3=CC(OS(=O)(O)=O)=C(O)C=C3)O)=O)([H])[C@H](O)CC(N)=O)N4[C@@](C(N[C@@H]([C@@H](C[C@@H](C(NC2[C@H](O)C)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)O)O)=O)([H])[C@@H](O)[C@@H](C)C4

Molecular Formula

C56H71N9O23S

Molecular Weight

1270.27

Precautions

H302, H312, H332

References & Citations

[1]Micafungin, From Wikipedia

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

BioRxiv. 2025 Feb 6:2025.02.05.636768.|Infect Drug Resist. 2022 Dec 15:15:7459-7473.|J Antimicrob Chemother. 2020 Aug 1;75 (8) :2133-2140.|J Microbiol Methods. 2021 Nov:190:106327.|Microorganisms. 2022 Dec 21;11 (1) :23.|Microorganisms. 2023 Jun 18;11 (6) :1608.|mSphere. 2018 Nov 14;3 (6) . pii: e00547-18.|mSphere. 2020 Oct 28;5 (5) :e00821-20.|Mycoses. 2021 Mar;64 (3) :282-291.|Antimicrob Agents Chemother. 2023 Aug 17;67 (8) :e0054323.|Appl Microbiol Biotechnol. 2025 Jan 24;109 (1) :21.|bioRxiv. 2024 May 14.|Chem Biol Interact. 2024 Jul 31:400:111179.|J Clin Microbiol. 2017 Jun;55 (6) :1883-1893.|NPJ Antimicrob Resist. 2025 Apr 17;3 (1) :31.|PLoS Negl Trop Dis. 2019 Aug 20;13 (8) :e0007681. |Sci Rep. 2017 Feb 17;7:42886.