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Sennidin B (Standard)

Sennidin B (Standard) is the analytical standard of Sennidin B. This product is intended for research and analytical applications. Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation [1][2].

Product Specifications

CAS Number

517-44-2

UNSPSC

12352005

Target

Akt; GLUT; HCV; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Others; PI3K/Akt/mTOR

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sennidin-b-standard.html

Smiles

O=C1C2=C(O)C=C(C(O)=O)C=C2[C@@]([C@]3([H])C4=CC(C(O)=O)=CC(O)=C4C(C5=C(O)C=CC=C35)=O)([H])C6=CC=CC(O)=C16

Molecular Formula

C30H18O10

Molecular Weight

538.46

References & Citations

[1]Furuta A, et al. Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 2015 Aug 7;16 (8) :18439-53.|[2]Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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