EeAChE-IN-3
EeAChE-IN-3 (compound YS3g) is an orally active, potent EeAChE and IL-6 inhibitor with IC50s of 0.54 μM, 0.49 μM, 8.54 μM and 0.57 μM for EeAChE, RatAChE, RatBuChE and IL-6, respectively. eeAChE-IN-3 improves STZ (HY-13753) (Streptozotocin; HY-13753) -induced learning and memory impairment in mice. eeAChE-IN-3 has the potential for Alzheimer's disease (AD) research[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/eeache-in-3.html
Smiles
O=C1C2=C(OC)C=C(OC)C=C2OC(CCCNN3CCNCC3)=C1
Molecular Formula
C18H25N3O4
Molecular Weight
347.41
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; IL-6
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