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IL2RB Polyclonal Antibody

Product Specifications

Background

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Abbreviation

IL2RB

UniProt

P14784

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein of human IL2RB

Target

CD122; CD122 antigen; High affinity IL 2 receptor beta subunit; High affinity IL 2 receptor subunit beta; High affinity IL-2 receptor subunit beta; IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; IL15RB; IL2 receptor; IL2RB; IL2RB; Interleukin 2 receptor beta; Interleukin-2 receptor subunit beta; P70 75; P70-75; P7075; p75

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Immunology; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

0.3 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

61kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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