KSR (Phospho-Ser392) Colorimetric Cell-Based ELISA Kit
The KSR (Phospho-Ser392) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor KSR (Phospho-Ser392) protein expression profile in cells. The kit can be used for measuring the relative amounts of KSR (Phospho-Ser392) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on KSR (Phospho-Ser392) .
Product Specifications
Synonyms
CAP kinase; HB; HB protein; Kinase suppressor of RAS-1; ceramide-activated protein kinase; kinase KSR1
Gene Name
KSR1
UniProt
Q8IVT5
Reactivity
Human, Mouse
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.
Molecular Weight
102160 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Kinase suppressor of Ras 1
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cell projection, ruffle membrane. Endoplasmic reticulum membrane. In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.
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