Keratin 19 Colorimetric Cell-Based ELISA Kit
The Keratin 19 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Keratin 19 protein expression profile in cells. The kit can be used for measuring the relative amounts of Keratin 19 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Keratin 19.
Product Specifications
Synonyms
Keratin type I cytoskeletal 19; Cytokeratin-19; CK-19; K19; KRT19
Gene Name
KRT19
UniProt
P08727
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level) . Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Molecular Weight
44106 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Keratin, type I cytoskeletal 19
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