Recombinant TNF receptor II Monoclonal Antibody

TNF receptor II (TNF-R2) is one of the receptors of TNF-α. The two receptors for TNF-α, TNF-R1 (55 kDa) and TNF-R2 (75 kDa), can mediate distinct cellular responses. In most cases, cytotoxicity elicited by TNF has been reported to act through TNF-R1. In contrast, TNF-R2 appears to be important in T cell signaling and responses to infection. TNF-R2 binds to distinct members of the TRAF family, leading to the activation of NF-κB. Soluble forms of both receptors have also been characterized which can bind TNF-α and may play an important role in immune disorders.

Soluble TNFR1B variant; Tumor necrosis factor receptor; tumor necrosis factor binding protein; CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR; TNF Receptor II; TNFRSF1B; p80 TNF-alpha receptor; Tumor Necrosis Factor Receptor II; Etanercept; P75tbpii; TNF-R2; TNFR2TNFR1B; TNFRII; TNF-RII; TNFR-II; CD120b antigen; p75 TNF receptor; soluble TNFR1B variant 1; TNF RII; TNFBRp80 TNF-alpha receptor; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily; member 1B; Tumor necrosis factor receptor type II; p80; Tumor Necrosis Factor Receptor II