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Bak Colorimetric Cell-Based ELISA Kit

The Bak Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Bak protein expression profile in cells. The kit can be used for measuring the relative amounts of Bak in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Bak.

Product Specifications

Synonyms

Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like 7 protein; BAK1; BAK; BCL2L7

Gene Name

BAK1

UniProt

Q16611

Reactivity

Human, Mouse

Tissue Specificity

Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.

Molecular Weight

23409 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Bcl-2 homologous antagonist/killer

Subcellular Location

Mitochondrion membrane; Single-pass membrane protein.

Frequently Asked Questions

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