20-Carboxy-Leukotriene B4
20-Carboxy-Leukotriene B4 (20-COOH LTB4) is a metabolite of Leukotriene B4 (LTB4; HY-107608). 20-Carboxy-Leukotriene B4 binds to the BLT1 receptor with high affinity. 20-Carboxy-Leukotriene B4 inhibits LTB4-mediated neutrophil responses (migration, degranulation, leukotriene biosynthesis).
Product Specifications
CAS Number
80434-82-8
Product Name Alternative
20-COOH LTB4
UNSPSC
12352211
Hazard Statement
H225-H315-H319-H335
Target
Drug Metabolite; Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/20-carboxy-leukotriene-b4.html
Concentration
272.89 μM * 250 μL in Ethanol
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(O)CCC[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\CCCCC(O)=O
Molecular Formula
C20H30O6
Molecular Weight
366.45
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P362+P364-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; LTB4
Frequently Asked Questions
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