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Anti-POLD1 Antibody

Boster Bio Anti-POLD1 Antibody (Catalog# A30643) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

POLD1; POLD; DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125

Gene Name

POLD1

UniProt

P28340

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human POLD1. Immunogen sequence location: 1051-1100

Clonality

Polyclonal

Tissue Specificity

Expressed across a panel of tissues, with high levels of expression in heart and lung.

Applications

WB, ELISA

Field of Research

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.

Molecular Weight

123631 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

DNA polymerase delta catalytic subunit

Subcellular Location

Nucleus.

Frequently Asked Questions

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