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Anti-MAEA/Emp Antibody

Boster Bio Anti-MAEA/Emp Antibody (Catalog# A08766-1) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

MAEA; EMP; HLC10; PIG5; Macrophage erythroblast attacher; Cell proliferation-inducing gene 5 protein; Erythroblast macrophage protein; Human lung cancer oncogene 10 protein; HLC-10

Gene Name

MAEA

UniProt

Q7L5Y9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human MAEA. Immunogen sequence location: 181-230

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Immunology, Innate Immunity, Macrophage/Inflammation, Myeloid, Stem Cells

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Molecular Weight

45287 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A08766-1

Product MSDS

https://www.bosterbio.com/msds?sku=A08766-1

Fragment

Rabbit IgG

Other Gene Names

Macrophage erythroblast attacher

Subcellular Location

Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Localized as nuclear speckled- like pattern.

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