Recombinant human Kallikrein 2/KLK2 protein
KLK2, also known as kallikerin-2 isoform1, is a secreted serine protease that is highly expressed in the human prostate gland. The enzyme is highly specific for cleavage after arginine residues. This protein is able to activate the urokinase-type plasminogen activator. It is inhibited by serpins such as protein C inhibitor, antichymotrypsin and plasminogen activator inhibitor. Recombinant human KLK2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Kallikrein related peptidase 2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2, Prostatic kallikrein 2
Expression System
Baculovirus
Antigen Species
Human, Canine, Influenza A-H3N2 (canine), Influenza A
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by absorbance at 280 nm)
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.2 kDa (246aa)
Additionnal Information
References & Citations
Frenette G., et al. (1997) Int J Cancer. 71:897-899.; ; Mikolajczyk SD., et al. (1999) Cancer Res. 59:3927-3930.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_005542
Uniprot Accession Number
P20151
Species
Human, Canine, Influenza A-H3N2 (canine), Influenza A
N Terminal Sequence
Ala
AA Sequence
Frequently Asked Questions
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