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Anti-GluR2/3 GRM3 Antibody

Boster Bio Anti-GluR2/3 GRM3 Antibody (Catalog # A04827) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<br><br>Akiko Momiyama, J. Physiol., May 2003; 549: 75 - 92.<br>Mako Narisawa-Saito, PNAS, Mar 1999; 96: 2461.<br>Karolina Wosik, Brain, Dec 2004; 127: 2636 - 2648.<br>Chong-Hyun Kim, PNAS, Sep 2001; 98: 11725.

Synonyms

Metabotropic glutamate receptor 3; mGluR3; GRM3; GPRC1C, MGLUR3

Gene Name

GRM3

UniProt

Q14832

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human GluR2/3.

Clonality

Polyclonal

Tissue Specificity

Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. .

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. .

Molecular Weight

98879 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Metabotropic glutamate receptor 3

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

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