ZK824190
Product Specifications
CAS Number
2254001-81-3
Target
PAI-1, Serine Protease
Related Pathways
Proteases/Proteasome, Metabolism
Purity
0.9884
Bioactivity
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA), with IC50 values of 237 nM for uPA, 1600 nM for tPA, and 1850 nM for Plasmin.
Smiles
O(C=1C=C(C=CC1)C2=CC(CN)=CC=C2)C=3N=C(O[C@@H](C(O)=O)CC)C(F)=CC3F
Molecular Formula
C22H20F2N2O4
Molecular Weight
414.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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