Anti-Sentrin-specific protease 1 SENP1 Antibody

Boster Bio Anti-Sentrin-specific protease 1 SENP1 Antibody catalog # A02156-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Sentrin-specific protease 1;3.4.22.68; Sentrin/SUMO-specific protease SENP1; SENP1

Gene Name

SENP1

UniProt

Q9P0U3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SENP1. AA range:1-50

Tissue Specificity

Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine. .

Applications

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032) . .