S-15261
S-15261 is an orally active and potent anti-hyperglycemic agent. S-15261 reduces hepatic glucose production through direct and insulin-sensitizing effects. S-15261 can be used for the research of insulin resistance syndrome[1][2].
Product Specifications
CAS Number
159978-02-6
UNSPSC
12352005
Target
Insulin Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-15261.html
Smiles
O=C(OCCNCC(OC)C1=CC=CC(C(F)(F)F)=C1)C2=CC=C(CCNC(CC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C=C2
Molecular Formula
C36H35F3N2O4
Molecular Weight
616.67
References & Citations
[1]Caüzac M, et al. S-15261, a new anti-hyperglycemic agent, reduces hepatic glucose production through direct and insulin-sensitizing effects. Biochem Pharmacol. 2005 Aug 15;70 (4) :527-34.|[2]Marquié G, et al. S15261, a novel agent for the treatment of insulin resistance. Studies on Psammomys obesus. Life Sci. 1997;61 (18) :1741-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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