Nampt activator-2
Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM) [1].
Product Specifications
CAS Number
[2237268-90-3]
UNSPSC
12352005
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nampt-activator-2.html
Purity
98.79
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CNN=C1)NC2=CC=C(S(=O)(C3=CC=C(C=C3)Cl)=O)C=C2
Molecular Formula
C17H15ClN4O3S
Molecular Weight
390.84
References & Citations
[1]Pinkerton AB, et al. Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators. Bioorg Med Chem Lett. 2021 Jun 1;41:128007.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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