PI3Kα-IN-19
PI3Kα-IN-19 (Compound 1) is a PI3Kα inhibitor with a targeted binding site at the p110α catalytic subunit. PI3Kα is one of the most common dysregulated kinases used in cancer research[1].
Product Specifications
CAS Number
885692-56-8
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kα-in-19.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(C#N)=CN1)NC2=CC=C(C(CC3)CCN3C(C4=C[N+]([O-])=CC=C4)=O)C=C2C5=CCCCC5
Molecular Formula
C28H28N6O3
Molecular Weight
496.56
References & Citations
[1]Shafiq, Muhammad et al. “A deep learning-based theoretical protocol to identify potentially isoform-selective PI3Kα inhibitors.” Molecular diversity, 10.1007/s11030-023-10799-0. 2 Feb. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα
Frequently Asked Questions
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