α-Glucosidase-IN-67

α-Glucosidase-IN-67 (compound 5k) is a potent α-Glucosidase inhibitor with IC50 values of 0.31, 4.51 µM for alpha-glucosidase and alpha-amylase, respectively. α-Glucosidase-IN-67 has the potential for the research of type-2 diabetes[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-67.html

Smiles

BrC1=CC=C(S(N2CCN(C3=CC=C(C(/C=C/C4=NC=CC=C4)=O)C=C3)CC2)(=O)=O)C=C1

Molecular Formula

C24H22BrN3O3S

Molecular Weight

512.42

References & Citations

[1]Hosseini Nasab N, et al. Exploring chalcone-sulfonyl piperazine hybrids as anti-diabetes candidates: design, synthesis, biological evaluation, and molecular docking study. Mol Divers. 2024 May 22.