MSP-3
MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].
Product Specifications
CAS Number
1820968-63-5
UNSPSC
12352005
Hazard Statement
H315, H319, H401
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/msp-3.html
Purity
98.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCC1=CC=CS1)NCC2=CC=C(C(OC)=C2)O
Molecular Formula
C16H19NO3S
Molecular Weight
305.39
Precautions
H315, H319, H401
References & Citations
[1]Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N- (4-Hydroxy-3-methoxybenzyl) -4- (thiophen-2-yl) butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7 (6) :737-48.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
TRPV1
Available Sizes
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