Integrin αD rabbit pAb
Integrin subunit alpha D (ITGAD) Homo sapiens This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
Product Specifications
Background
Synonyms
ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d
Gene ID
3681
UniProt
Q13349
Cellular Locus
Membrane; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ITGAD. AA range:901-950
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
127kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4190-1.pdf
Observed Molecular Weight
127 kD
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d
Gene ID (Human)
3681
SwissProt (Human)
Q13349
Available Sizes
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