Interleukin-4 (Human, Recombinant)

<strong>Interleukin-4 (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010311_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Interleukin-4 (Human, Recombinant) expressed in CHO. This protein acts as a potent lymphoid cell growth factor that stimulates the growth and survivability of B-cells and T-cells._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Dong C, Fu T, Ji J, Li Z, Gu Z. The role of interleukin-4 in rheumatic_x000D_ diseases. Clin Exp Pharmacol Physiol. 2018 Aug;45(8):747-754._x000D_ _x000D_ 2: Braddock M, Hanania NA, Sharafkhaneh A, Colice G, Carlsson M. Potential Risks_x000D_ Related to Modulating Interleukin-13 and Interleukin-4 Signalling: A Systematic_x000D_ Review. Drug Saf. 2018 May;41(5):489-509._x000D_ _x000D_ 3: Sequeida A, Maisey K, Imarai M. Interleukin 4/13 receptors: An overview of_x000D_ genes, expression and functional role in teleost fish. Cytokine Growth Factor_x000D_ Rev. 2017 Dec;38:66-72._x000D_ _x000D_ 4: Wachholz S, Knorr A, Mengert L, Plümper J, Sommer R, Juckel G, Friebe A._x000D_ Interleukin-4 is a participant in the regulation of depressive-like behavior._x000D_ Behav Brain Res. 2017 May 30;326:165-172._x000D_ _x000D_ 5: Świerczek-Lasek B, Neska J, Kominek A, Tolak Ł, Czajkowski T, Jańczyk-Ilach_x000D_ K, Stremińska W, Piwocka K, Ciemerych MA, Archacka K. Interleukin 4 Moderately_x000D_ Affects Competence of Pluripotent Stem Cells for Myogenic Conversion. Int J Mol_x000D_ Sci. 2019 Aug 13;20(16):3932._x000D_ _x000D_ 6: Maes T, Joos GF, Brusselle GG. Targeting interleukin-4 in asthma: lost in_x000D_ translation? Am J Respir Cell Mol Biol. 2012 Sep;47(3):261-70._x000D_ _x000D_ 7: Chomarat P, Banchereau J. Interleukin-4 and interleukin-13: their_x000D_ similarities and discrepancies. Int Rev Immunol. 1998;17(1-4):1-52._x000D_ _x000D_ 8: Ul-Haq Z, Naz S, Mesaik MA. Interleukin-4 receptor signaling and its binding_x000D_ mechanism: A therapeutic insight from inhibitors tool box. Cytokine Growth_x000D_ Factor Rev. 2016 Dec;32:3-15._x000D_ _x000D_ 9: Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP._x000D_ Regulation of inflammation by interleukin 4: a review of "alternatives". J_x000D_ Leukoc Biol. 2012 Oct;92(4):753-64._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27595549/">_x000D_ 10: Lühmann T, Spieler V, Werner V, Ludwig MG, Fiebig J, Mueller TD, Meinel L._x000D_ Interleukin-4-Clicked Surfaces Drive M2 Macrophage Polarization. Chembiochem._x000D_ 2016 Nov 17;17(22):2123-2128.</a>_x000D_ _x000D_ <strong>Products Related to Interleukin-4 (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>