MK-2206 Dihydrochloride
Product Specifications
CAS Number
1032350-13-2
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
C1CC (C1) (C2=CC=C (C=C2) C3=C (C=C4C (=N3) C=CN5C4=NNC5=O) C6=CC=CC=C6) N.Cl.Cl
Molecular Formula
C25H21N5O.2HCl
Additionnal Information
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2.
Storage Conditions
2 years -80 in solvent
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