L-Valine-13C5,15N, d2

L-Valine-13C5,15N, d2 ((S) -Valine-13C5,15N, d2) is the deuterium, 13C-, and 15N-labeled L-Valine (HY-N0717) . L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Product Specifications

CAS Number

[201417-09-6]

Product Name Alternative

(S) -Valine-13C5,15N, d2

UNSPSC

12352211

Target

Akt; Arginase; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

[13CH3][13C]([13CH3])([2H])[13C@@]([15NH2])([2H])[13C](O)=O

Molecular Formula

13C5H9D2 15NO2

Molecular Weight

125.12

References & Citations

[1]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36.|[2]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.|[3]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6.