INCB159020

2923669-20-7

Ras

MAPK|||GPCR/G Protein

INCB159020 is an orally active inhibitor of KRAS G12D, exhibiting a KRAS G12D SPR value of 2.2 nM. It demonstrates anti-tumor activity.

[C@@H](C)(C=1N(C2=C(C(=NC=3C2=CC(CCC#N)=C(C3F)C4=C(C)C(Cl)=CC=C4)C=5C=NC(C)=CN5)C1)[C@H]6[C@@]7(C[C@]6(NC7)[H])[H])N8C(=O)COCC8

C37H35ClFN7O2

664.171

Cool pack

-20°C