Trimedoxime
Trimedoxime (TMB-4) is a potent reactivator of AChE. Trimedoxime shows potency in inducing oxidative stress, with the IC50 of 22 mM[1].
Product Specifications
CAS Number
56-97-3
Product Name Alternative
TMB-4
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trimedoxime.html
Smiles
O/N=C/C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1.[Br-].[Br-]
Molecular Formula
C15H18Br2N4O2
Molecular Weight
446.14
References & Citations
[1]Nela Váňová, et al. In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells. 2023 Dec 18; 36 (12) : 1912–1920.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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