BTK inhibitor 19
BTK inhibitor 19 is a highly selective, covalent BTK inhibitor (IC50 = 2.7 nM) .
Product Specifications
CAS Number
[2557174-19-1]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-inhibitor-19.html
Solubility
10 mM in DMSO
Smiles
NC(C1=C(C2=CC=C(C(NC3=NC=CC(C(F)(F)F)=C3)=O)C=C2)N=C([C@@H]4CCCCN4C(C=C)=O)N1N)=O
Molecular Formula
C25H24F3N7O3
Molecular Weight
527.50
References & Citations
[1]Ma C, et al. Discovery of 1-Amino-1H-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitors. J Med Chem. 2021 Nov 11;64 (21) :16242-16270.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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