SIRT3 Antibody
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
Product Specifications
UniProt
Q9NTG7
Host
Mouse
Immunogen
Recombinant full-length human SIRT3 protein was used as the immunogen for the SIRT3 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, FACS, IF, WB
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SIRT3 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/51595572/datasheet/v9646-20ug.pdf
CAS Number
9007-83-4
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