JNK-IN-8
JNK-IN-8 is a potent, selective, pan-JNK inhibitor with IC50 of 4.7 nM, 18.7 nM and 1 nM for JNK1, JNK2 and JNK3, respectively; exhibits exceptional selectivity based upon KinomeScan and enzymatic profiling; inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively.
Product Specifications
CAS Number
1410880-22-6
Product Name Alternative
JNK-IN-8 | c-Jun N-terminal Kinase Inhibitor XVI
Field of Research
Signal Transduction
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 35 mg/mL
Smiles
CN (C/C=C/C (NC1=CC=CC (C (NC2=CC=C (C (C) =C2) NC3=NC=CC (C4=CN=CC=C4) =N3) =O) =C1) =O) C
Molecular Formula
C29H29N7O2
Molecular Weight
507.6
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, 3-[[4- (dimethylamino) -1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4- (3-pyridinyl) -2-pyrimidinyl]amino]phenyl]-
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Monkey Endocrine gland vascular endothelial growth factor ELISA kit
Chicken Ankyrin repeat domain containing protein 46 (ANKRD46) ELISA Kit
Recombinant Drosophila simulans Cytochrome c oxidase subunit 2 (mt:CoII), partial