Bcl6 Antibody
Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( LH ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Product Specifications
UniProt
P41182
Host
Mouse
Immunogen
Recombinant human BCL6 protein was used as the immunogen for the Bcl6 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Applications
FACS, IF
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Bcl6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Bcl6 antibody is available for research use only.
CAS Number
9007-83-4
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