AS3 Antibody / PDS5B
Sister chromatid cohesion protein PDS5 homolog B (PDS5B), also called Androgen-induced prostate proliferative shutoff-associated protein AS3, or simply 'AS3, ' is a protein that in humans is encoded by the PDS5B gene. This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
Q9NTI5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E. coli-derived recombinant human protein (amino acids Q499-Q1424) was used as the immunogen for the AS3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This AS3 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the AS3 antibody should be determined by the researcher.
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