c-Kit(Phospho-Tyr719) Rabbit Polyclonal Antibody

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor| also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors| mast cell disease| acute myelogenous lukemia| and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

c-Kit ;Tyr719; Mast/stem cell growth factor receptor Kit; SCFR; EC 2.7.10.1; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117