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GRK2 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

BARK1; ADRBK1; BETA-ARK1

Swiss Prot

P25098

Reactivity

Human

Immunogen

A synthetic peptide of human GRK2

Conjugation

Unconjugated

Applications

WB, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot detection of GRK2 in Hela, A549, HL-60, U2OS cell lysates using GRK2 antibody (1:1000 diluted) .

Host or Source

Rabbit

Available Sizes

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