PAI1 Recombinant Rabbit mAb

Product Specifications

Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

CAS Number

9000-83-3

Structure Composition

Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Product Name Alternative

PAI; PAI1; PAI-1; PLANH1

Swiss Prot

P05121

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PAI1

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC, IP

Purity

Affinity Purification

Modification

Unmodification

Molecular Weight

45 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

IgG

Applications Notes

Western blot (WB) analysis of PAI1 Recombinant Rabbit mAb at 1:500 dilution Lane1:COS-7 whole cell lysate (30ug) Lane2:U251 whole cell lysate (30ug) Lane3:A549 whole cell lysate (30ug)