DYNC1I1 polyclonal antibody

Product Specifications

Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

CAS Number

9007-83-4

Structure Composition

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

DYNC1I1; DNCI1; DNCIC1

Swiss Prot

O14576

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human DYNC1I1 (NP_001129028.1) .

Conjugation

Unconjugated

Applications

WB, IHC

Dilution

WB,1:200 - 1:2000|IHC,1:20 - 1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .