ALKBH4 polyclonal antibody
Product Specifications
Background
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1, thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N (6-methyladenosine DNA, thereby regulating Polycomb silencing (By similarity.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ALKBH4; ABH4
Swiss Prot
Q9NXW9
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ALKBH4 (NP_060091.1) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
Refer to figures
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Applications Notes
Immunofluorescence analysis of A549 cells using ALKBH4 antibody . Blue: DAPI for nuclear staining.
Host or Source
Rabbit
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1048891 100 µL
Phospho-c-Abl (Tyr89) Rabbit Polyclonal Antibody (RBITC)
Sign In for Pricing
View Details LV669571 1.0 µg DNA
ASB17 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details