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FNDC4 polyclonal antibody

Product Specifications

Background

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

FRCP1

Swiss Prot

Q9H6D8

Reactivity

Mouse, Rat

Immunogen

Recombinant protein of human FNDC4

Conjugation

Unconjugated

Applications

WB

Dilution

WB 1:500 - 1:2000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 25 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

FNDC4 polyclonal antibody detects endogenous levels of FNDC4 protein.

Applications Notes

Western blot analysis of extracts of various cell lines, using FNDC4 antibody.

Host or Source

Rabbit

Available Sizes

Curated Selection

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