CNNM2 polyclonal antibody

Product Specifications

Background

Cyclin M2 is a protein in humans that is encoded by the CNNM2 gene. This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2; CNNM2; ACDP2

Swiss Prot

Q9H8M5

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 580-630 of Human CNNM2.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 96 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CNNM2 polyclonal antibody detects endogenous levels of CNNM2 protein.

Applications Notes

Western blot (WB) analysis of CNNM2 polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:U-87MG whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:HepG2 whole cell lysate (40ug)