RPL22 polyclonal antibody

Product Specifications

Background

Ribosomal Protein L22 is also known as heparin-binding protein HBp15, because it binds heparin in the submandibular gland and brain. This small protein is also associated with two small nuclear RNAs called EBERs (Epstein- Barr encoded RNAs) . These RNAs are synthesized in large amounts by human B lymphocytes infected with Epstein-Barr virus (EBV) . Ribosomal protein L22, like L4, contains a globular domain that sits on the surface of the large ribosomal subunit and an extended loop that penetrates its core. These extensions contact multiple domains of 23S rRNA, indicating a potential, but not essential, role in rRNA folding during ribosomal assembly.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

60S ribosomal protein L22; EBER-associated protein; EAP; Epstein-Barr virus small RNA-associated protein; Heparin-binding protein HBp15; RPL22

Swiss Prot

P35268

Reactivity

Human, Mouse

Immunogen

A synthetic peptide corresponding to residues in Human RPL22.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 15 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RPL22 polyclonal antibody detects endogenous levels of RPL22 protein.

Applications Notes

Western blot (WB) analysis of Ribosomal Protein L22 (L91) pAb at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:Myla2059 whole cell lysate (30ug) Lane3:A2780 whole cell lysate (40ug)