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SGCA polyclonal antibody

Product Specifications

Background

Sarcoglycan alpha (SGCA) Homo sapiens This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

CAS Number

9007-83-4

Structure Composition

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Product Name Alternative

SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2

Swiss Prot

Q16586

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SGCA. AA range:161-210

Conjugation

Unconjugated

Applications

WB, ELISA

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Modification

Unmodification

Molecular Weight

~ 43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Sarcoglycan α Polyclonal Antibody detects endogenous levels of Sarcoglycan α protein.

Applications Notes

Western blot analysis of lysates from HeLa, HepG2, and Jurkat cells, using SGCA Antibody. The lane on the right is blocked with the synthesized peptide.

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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