BMP-8A (Q299) polyclonal antibody

Product Specifications

Background

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity) . Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Product Name Alternative

Bone morphogenetic protein 8A; BMP-8A; BMP8A

Swiss Prot

Q7Z5Y6

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide, corresponding to Human BMP-8A.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:5000~1:10000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 45 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

BMP-8A (Q299) polyclonal antibody detects endogenous levels of BMP-8A protein.

Applications Notes

Western blot (WB) analysis of BMP-8A polyclonal antibody at 1:5000 dilution Lane1:Jurkat whole cell lysate (40ug) Lane2:Hela whole cell lysate (40ug) Lane3:MCF-7 whole cell lysate (40ug) Lane4:PC12 whole cell lysate (40ug) Lane5:CT-26 whole cell lysate (40ug)