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CHRND Polyclonal Antibody

This is a CHRND Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS) . Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

CHRND, ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Gene ID

1144

Swiss Prot

Q07001

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human CHRND

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

7kDa/27kDa/31kDa

Observed Molecular Weight

32kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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