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CD43 monoclonal antibody

Product Specifications

Background

CD43, also known as leukosialin and sialophorin, is a type I transmembrane sialylated, negatively charged mucin that is expressed on the surface of most hematopoietic cells. CD43 plays an important role in T lymphocyte function by negatively regulating antigen-specific T cell activation and interfering with cellular adhesion and proliferation. It also has been reported that CD43 is involved in viral clearance. Aberrant expression of CD43 is associated with several diseases, such as Wiskott-Aldrich syndrome and acute leukemia.

CAS Number

9007-83-4

Structure Composition

Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Product Name Alternative

CD43; Leukosialin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD43

Swiss Prot

P16150

Reactivity

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within human CD43. The exact sequence is proprietary.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC (1/100 - 1/300)

Purity

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 40 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Recognizes endogenous levels of CD43 protein.

Host or Source

Mouse

Available Sizes

Frequently Asked Questions

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