Mouse anti human collagen IV a5 Chain
Product Specifications
Background
Alport's syndrome, an inherited disease, shows absence or reduction of the a5 chain in the glomerular, tubular and bowman's capsular basement membranes. Normal human kidney has a1 (TV) to a6 (IV) chains in the renal basement membrance.
CAS Number
9007-83-4
Structure Composition
Appearance:Solution, Monoclonal antibodies were purified by affinity chromatography.0.02% ProClin 300 is added for preservation.
Immunogen
Synthetic peptides NC1 domain of type lV collagen.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Purity
Monoclonal antibodies were prepared by the mouse splenocytes fusion method.
Modification
Unmodification
Storage Conditions
Store at 4°C.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
8A12D2-2 is specific to NC1 domain of a1 (IV) .
Applications Notes
FITC fluorescence a5 chain is observed in the GBM, part of the TBM and Bowman's capsular.
Host or Source
Mouse
Available Sizes
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