LZK monoclonal antibody
Product Specifications
Background
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
CAS Number
9007-83-4
Structure Composition
Mouse IgM. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
LZK; Mitogen-activated protein kinase kinase kinase 13; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK
Swiss Prot
O43283
Reactivity
Human
Immunogen
Recombinant fusion protein of human LZK. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB (1/500 - 1/1000)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of LZK protein.
Applications Notes
Western blot analysis of LZK expression in NCIH460 (A) whole cell lysates.
Host or Source
Mouse
Available Sizes
Curated Selection
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