CYP11B1/2 rabbit pAb
Cytochrome P450 family 11 subfamily B member 1 (CYP11B1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Gene ID
1584
UniProt
P15538
Cellular Locus
Mitochondrion inner membrane ; Peripheral membrane protein.
Host
Rabbit
Species Reactivity
Human
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CYP11B1/2. AA range:61-110
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
58kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES3954-1.pdf
Observed Molecular Weight
58 kD
Subcellular Location
Mitochondrion inner membrane ; Peripheral membrane protein .
Other Product Names
Gene ID (Human)
1584
SwissProt (Human)
P15538
Available Sizes
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