Phospho-AURKA-T288 polyclonal antibody
Product Specifications
Background
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
AURKA; AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7
Swiss Prot
O14965
Reactivity
Human
Immunogen
A synthetic phosphorylated peptide around T288 of human AURKA (NP_003591.2) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylated
Molecular Weight
48kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Phosphorylated
Host or Source
Rabbit
Available Sizes
Curated Selection
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TAF2, CT (TAF2, CIF150, TAF2B, Transcription initiation factor TFIID subunit 2, 150kD cofactor of initiator function, RNA polymerase II TBP-associated factor subunit B, TBP-associated factor 150kD, Transcription initiation factor TFIID 150kD subunit) (PE)
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